Endocrine Abstracts

Objective: The thiazolidinediones are new and potentially useful developments in the treatment of type 2 diabetes and impaired glucose tolerance. We tested the effects of the thiazolidinedione, rosiglitazone on blood pressure in normotensive type 2 diabetes.Methods: After receiving approval from the local ethics committee, 25 normotensive diabetic patients were were enrolled to the study. Before the rosiglitazone treatment we measured plasma glucose, HbA...

Objective: Thiazolidinediones (TZDs) have become a powerful tool for lowering insulin resistance. The problem of cardiovascular adverse events including fluid retention and risk of heart failure, although of a low incidence, should be well known and recognized. We aimed to evaluate the effects of rosiglitazone treatment on cardiac function and show whether these effects are reversible when we continued this treatment.Methods: Fourty-six type 2 diabetic p...